The most difficult Python questions:

• What is the Global Interpreter Lock (GIL)? Why is it important?

• Define self in Python?

• What is pickling and unpickling in Python?

• How do you reverse a list in Python?

• What does break and continue do in Python?

• Can break and continue be used together?

• Explain generators vs iterators.

• How do you access a module written in Python from C?

• What is the difference between a List and a Tuple?

• What is __init__() in Python?

• What is the difference between a mutable data type and an immutable data type?

• Explain List, Dictionary, and Tuple comprehension with an example.

• What is monkey patching in Python?

• What is the Python “with” statement designed for?

• Why use else in try/except construct in Python?

• What are the advantages of NumPy over regular Python lists?

• What is the difference between merge, join and concatenate?

• How do you identify and deal with missing values?

• Which all Python libraries have you used for visualization?

• What is the most difficult Python question you have ever encountered?